Key points in this article:
- The redefinition of hemp under federal law also outlaws interstate commerce in most cannabis seeds and genetics.
- Seeds for cannabis cultivars that create flower with 0.3%THC or more are illegal to ship across state lines starting Nov. 12.
- In response, seed companies are diversifying to other states. But operators including cultivators and retailers may soon see their offerings severely limited.
Laura Campanella lives and works in Colorado, but she’s spending part of her summer in Oklahoma, launching a cannabis clone and tissue culture business.
Expanding to a new state allows the CEO of Colorado-based cannabis genetics outfit Brothers Grimm Seeds to diversify her business. But Campanella’s new concept is also a response to changes in federal law that will soon make seeds from high-THC cannabis cultivars illegal to ship across state lines.
A redefinition of hemp under federal law, scheduled to take effect Nov. 12, spells the end of Farm Bill protections for many hemp-derived THC products across the country: low-dose beverages as well as THCA flower and delta-8 THC gummies, vapes and other products sold at gas stations and smoke shops.
But the hemp ban also creates a major complication for the legal cannabis industry. Seeds from cannabis cultivars that produce flower with more than 0.3% THC are no longer legal to ship out of state.
Although seed purchases will likely continue in legal states, the changes threaten to shutter some seed banks and genetics companies , observers say, while creating supply-chain issues for cannabis cultivators and retailers.
“If this language goes through, we will need pop-up shops to sell seeds in every state where it’s legal,” Campanella said. “Which is why we’re also offering clones and tissue culture, because that’s not included in the bill.”
When are cannabis seeds and clones illegal to ship across state lines?
The new regulations classify seeds based on the THC potential of the mother plant. Genetic material such as seeds and clones are rendered illegal if the final product crosses the threshold.
For the moment, seeds are still shipping under the 2018 Farm Bill’s status quo. But the clock is ticking for enterprises like Brothers Grimm – and for cannabis cultivators who fear supply chain disruptions if out-of-state access to genetics is prohibited.
Most of the cannabis industry remains largely oblivious to the impending shutdown of the interstate genetics market, said Ryan Power, cofounder of Sebastopol, California-based breeder Atlas Seed.
Without federal intervention in the way of a carve-out for seeds or an overall moratorium, many seed providers will simply be shuttered come November, he added.
“We are operating legally now, but if that changes, it will mess up the legal licensed industry in every state,” said Power, whose clientele includes seed banks as well as licensed commercial cultivators.
“Consumers are going to lose choice, and it will be a major shutdown for most people.”
What are cannabis seed banks doing to stay legal after the federal hemp ban?
Sagui Silber has already recalibrated Silberhaze Genetics, his Ohio genetics company, of state Senate Bill 56, which tightened cannabis supervision in that state while also restricting hemp-derived THC products to licensed cannabis retailers.
Formerly a seed bank, Silberhaze is now focused on the branding, preservation and IP protection of elite plant genetics.
That’s because seed businesses hoping to stay compliant in this new environment must have airtight documentation, he said.
“You have to prove where this stuff comes from, so it’s very important to have records, even to the point where you have breeder names,” Silber said.
“Small businesses will have to work with better records and a better chain of custody,” he added. “We want that documentation ourselves, because we don’t want to be dealing with shady sources.”
To avoid seizures and other legal fallout, seed entrepreneurs must “get all their ducks in a row” before the new regulations take effect, Silber said.
“Audit all your stuff immediately, and classify what you can classify,” Silber said. “Take inventory, document your lineage, preserve breeder records, and organize any cannabinoid or terpene data you already have. If regulations shift, you’ll be in a much better position to understand what may be affected and make informed decisions.”
Does federal marijuana rescheduling affect cannabis genetics?
Silber believes U.S. Drug Enforcement Administration registration may be necessary for companies engaged in research.
But for now, seed houses can’t register with the DEA like state-licensed medical cannabis operators can. Such an option is closed to seed banks, nurseries or genetics companies, said Jim Ickes, an attorney and partner with Frantz Ward’s cannabis practice group in Cleveland.
“Seed-related activity may be happening inside broader state-licensed medical marijuana operations, as some states allow dispensaries or registered medical operators to sell seeds, clones or home-cultivation materials,” he said.
“But that is different from the DEA creating a freestanding seed bank registration category.”
Some genetics operators are already changing business practices to comply with the new law. According to Ickes, they must answer questions including:
- Which of our lines produce plants over 0.3% total THC?
- Which seeds survive as hemp after Nov. 12, 2026, and which don’t?
- What does our catalog look like once we sort it against the viable-seed exclusion?
Ickes also understands confusion from clients who believed federal rescheduling of medical marijuana would clarify their story with financial institutions. However, the latest regulatory language has moved those conversations beyond the basics of classification, he said.
“Banks ask whether this specific revenue stream is lawful, whether it ties to state-licensed activity, or whether there’s interstate-commerce risk,” said Ickes.
“After November, a seed bank selling drug-type genetics can’t answer the first question with the hemp definition. It has to point to a lawful state cannabis channel instead. Seed banks dealing in genuine industrial-hemp seed keep the cleaner story.”
“The rest need a new one.”
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What’s the future of cannabis genetics?
Campanella is part of a new coalition of fellow breeders, farmers and researchers that’s arguing seeds are better defined as agricultural inputs than controlled substances. To that end, seeds should be managed by the U.S. Department of Agriculture, leaving the DEA to focus its enforcement efforts elsewhere.
“How do you regulate something on what it might be one day?” said Campanella. “Our preference is to have that language removed, or (have seeds) regulated by the USDA as a hemp product.”
But in the meantime, Campanella is restructuring Brothers Grimm to operate outside the reach of shifting federal oversight. The company plans to maintain its Colorado seed operation while positioning its Oklahoma tissue culture facility as a hedge against federal prohibition of cannabis seeds.
As she explained: “If things develop in a way where we can’t focus on interstate shipping, we’ll have other resources to meet people’s needs without getting ourselves in trouble.”


